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Cloning and functional analysis of multiply spliced mRNA species of human immunodeficiency virus type 1

1 Jun 1990

Abstract excerpt

We have used the polymerase chain reaction technique to clone the small multiply spliced mRNA species produced after infection of human cells by a molecular clone of human immunodeficiency virus type 1 (HIV-1). We identified six Rev-expressing mRNAs, which were generated by the use of two splice acceptors located immediately upstream of the rev AUG. The class of small mRNAs included 12 mRNAs expressing Tat, Rev,...

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PMID: 2335812
DOI: 10.1128/jvi.64.6.2519-2529.1990

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