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Article

Fibroblast growth factor 10 (Fgf10) invalidation results in anorectal malformation in mice.

Journal of pediatric surgery - 1 Mar 2004

Fairbanks Timothy J, De Langhe Stijn, Sala Frederic G, Warburton David, Anderson Kathryn D, Bellusci Saverio, Burns R Cartland

Abstract excerpt

BACKGROUND/PURPOSE: Anorectal malformations occur in 1 per 4,000 live births and represent a surgical challenge. Although critically important, the basic mechanisms of normal anorectal union are incompletely understood. Fgf10 signaling is known to serve a key role in mesenchymal/epithelial interactions in many organ systems including the gastrointestinal tract (GIT). The authors therefore hypothesized that Fgf10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15017552
DOI: 10.1016/j.jpedsurg.2003.11.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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