Article
Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.
PLoS genetics - 1 Jun 2007
Yang Chao-Tsung, Hindes Anna E, Hultman Keith A, Johnson Stephen L
Abstract excerpt
The establishment of a single cell type regeneration paradigm in the zebrafish provides an opportunity to investigate the genetic mechanisms specific to regeneration processes. We previously demonstrated that regeneration melanocytes arise from cell division of the otherwise quiescent melanocyte precursors following larval melanocyte ablation with a small molecule, MoTP. The ease of ablating melanocytes by MoTP...
Topics
- Animals
- Cell Differentiation
- Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing)
- Melanocytes
- Molecular Sequence Data
- Mutation
- RNA Helicases
- Regeneration
- Zebrafish
- Zebrafish Proteins
