Article
Beta-adrenergic receptor blockade and the angiotensin-converting enzyme deletion polymorphism in patients with chronic heart failure.
European journal of heart failure - 1 Jan 2004
de Groote Pascal, Helbecque Nicole, Lamblin Nicolas, Hermant Xavier, Amouyel Philippe, Bauters Christophe, Dallongeville Jean
Abstract excerpt
BACKGROUND: Beta-adrenergic receptor blockade is an established treatment of chronic heart failure (HF). Previous studies have suggested a potential pharmacogenetic interaction between beta-blocker therapy and the angiotensin-converting enzyme (ACE) I/D polymorphism in patients with HF. AIMS: We designed this study to analyze changes in myocardial function of HF patients in response to beta-blocker therapy as a...
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