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Article

Angiotensin-converting-enzyme gene polymorphism and heart failure: a case-control study.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2000

Covolo L, Gelatti U, Metra M, Donato F, Nodari S, Pezzali N, Dei Cas L, Nardi G

Abstract excerpt

Heart failure (HF) is the final outcome of virtually all cardiovascular diseases and is a major and increasingly serious public health problem. The renin-angiotensin system plays an important role in the pathogenesis of cardiovascular disease. Insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) has attracted significant attention; it has been extensively investigated in a spectrum of...

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Source

Identifiers

PMID: 14602526
DOI: 10.1080/13547500310001599052

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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