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Article

Cellular dynamics shape recombination frequency in coronaviruses

27 Sept 2024

Abstract excerpt

Coronavirus genomes have evolutionary histories shaped extensively by recombination. Yet, how often recombination occurs at a cellular level, or the factors that regulate recombination rates, are poorly understood. Utilizing experimental co-infections with pairs of genetically distinct coronaviruses, we found that recombination is both frequent and rare during coinfection. Recombination occurred in every instance...

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PMID: 39331680
DOI: 10.1371/journal.ppat.1012596

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