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Article

Epistatic effect of IL1A and IL4RA genes on the risk of atopy.

The Journal of allergy and clinical immunology - 1 Mar 2004

Adjers Kati, Pessi Tanja, Karjalainen Jussi, Huhtala Heini, Hurme Mikko

Abstract excerpt

BACKGROUND: Several studies have demonstrated a linkage or association of the atopic phenotype with T-cell cytokine genes involved in the regulation of the TH1/TH2 balance (eg, IL4, IL13, and their common receptor, IL4RA). We have recently shown that polymorphism of the pro-inflammatory cytokine IL1A gene is strongly associated with atopy. OBJECTIVE: We now examined whether the polymorphisms of IL1A (G/T at...

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Source

Identifiers

PMID: 15007345
DOI: 10.1016/j.jaci.2003.12.582

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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