Article
Epistatic effect of TLR4 and IL4 genes on the risk of asthma in females.
International archives of allergy and immunology - 1 Nov 2005
Adjers Kati, Karjalainen Jussi, Pessi Tanja, Eklund Carita, Hurme Mikko
Abstract excerpt
BACKGROUND: Many studies have demonstrated a connection between asthma and T-cell cytokine genes, such as genes coding for interleukin-4 (IL4) and IL-13, which are involved in the regulation of the TH1/TH2 balance. The toll-like receptor 4 (TLR4), the principal receptor for bacterial endotoxin, has attracted attention as a potential risk factor for asthma. We examined whether the polymorphisms of the TLR4 (A/G at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.