[Impact of mutation rate on the adaptation of gut bacteria].

Abstract excerpt

To study the role of mutator bacteria in the evolution of bacterial populations, we followed the impact of the mutation rate of Escherichia coli strains in the colonisation of the gut of axenic mice and the evolution of the mutation rate of bacterial populations living in the gut. We show that mutator bacteria have an advantage during the colonization. This adaptive advantage comes from their ability to generate...

Topics

• Adaptation, Physiological
• Adenosine Triphosphatases
• Animals
• Anti-Bacterial Agents
• Bacterial Proteins
• DNA-Binding Proteins
• Enterobacteriaceae
• Escherichia coli
• Escherichia coli Proteins
• Evolution, Molecular
• Germ-Free Life