The evolution of mutator genes in bacterial populations: the roles of environmental change and timing.

Abstract excerpt

Recent studies have found high frequencies of bacteria with increased genomic rates of mutation in both clinical and laboratory populations. These observations may seem surprising in light of earlier experimental and theoretical studies. Mutator genes (genes that elevate the genomic mutation rate) are likely to induce deleterious mutations and thus suffer an indirect selective disadvantage; at the same time,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacteria
• Share to Computer Simulation
• Share to Environment