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Article

COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation.

Traffic (Copenhagen, Denmark) - 1 Feb 2006

Shestakova Anna, Zolov Sergey, Lupashin Vladimir

Abstract excerpt

Defects in conserved oligomeric Golgi (COG) complex result in multiple deficiencies in protein glycosylation. On the other hand, acute knock-down (KD) of Cog3p (COG3 KD) causes accumulation of intra-Golgi COG complex-dependent (CCD) vesicles. Here, we analyzed cellular phenotypes at different stages of COG3 KD to uncover the molecular link between COG function and glycosylation disorders. For the first time, we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16420527
DOI: 10.1111/j.1600-0854.2005.00376.x

Genes

COG3
COG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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