Article
SNPWave: a flexible multiplexed SNP genotyping technology.
Nucleic acids research - 5 Mar 2004
van Eijk Michiel J T, Broekhof José L N, van der Poel Hein J A, Hogers René C J, Schneiders Harrie, Kamerbeek Judith, Verstege Esther, van Aart Joris W, Geerlings Henk, Buntjer Jaap B, van Oeveren A Jan, Vos Pieter
Abstract excerpt
Scalable multiplexed amplification technologies are needed for cost-effective large-scale genotyping of genetic markers such as single nucleotide polymorphisms (SNPs). We present SNPWave, a novel SNP genotyping technology to detect various subsets of sequences in a flexible fashion in a fixed detection format. SNPWave is based on highly multiplexed ligation, followed by amplification of up to 20 ligated probes in...
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