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Article

Complexity reduction of polymorphic sequences (CRoPS): a novel approach for large-scale polymorphism discovery in complex genomes.

PloS one - 14 Nov 2007

van Orsouw Nathalie J, Hogers René C J, Janssen Antoine, Yalcin Feyruz, Snoeijers Sandor, Verstege Esther, Schneiders Harrie, van der Poel Hein, van Oeveren Jan, Verstegen Harold, van Eijk Michiel J T

Abstract excerpt

Application of single nucleotide polymorphisms (SNPs) is revolutionizing human bio-medical research. However, discovery of polymorphisms in low polymorphic species is still a challenging and costly endeavor, despite widespread availability of Sanger sequencing technology. We present CRoPS as a novel approach for polymorphism discovery by combining the power of reproducible genome complexity reduction of AFLP with...

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Identifiers

PMID: 18000544
DOI: 10.1371/journal.pone.0001172
PMCID: PMC2048665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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