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Article

Immune defects in 28-kDa proteasome activator gamma-deficient mice.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2004

Barton Lance F, Runnels Herbert A, Schell Todd D, Cho Yunjung, Gibbons Reta, Tevethia Satvir S, Deepe George S, Monaco John J

Abstract excerpt

Protein complexes of the 28-kDa proteasome activator (PA28) family activate the proteasome and may alter proteasome cleavage specificity. Initial investigations have demonstrated a role for the IFN-gamma-inducible PA28alpha/beta complex in Ag processing. Although the noninducible and predominantly nuclear PA28gamma complex has been implicated in affecting proteasome-dependent signaling pathways, such as control...

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Identifiers

PMID: 15004203
DOI: 10.4049/jimmunol.172.6.3948

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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