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Article

'Interleukin-4 gene polymorphism and its relation to periodontal disease in a Brazilian population of African heritage'.

Journal of dentistry - 1 Mar 2004

Pontes Carla Cruvinel, Gonzales Jose R, Novaes Arthur Belém, Taba Júnior Mário, Grisi Márcio Fernando M, Michel Joerg, Meyle Joerg, de Souza Sérgio Luís Scombatti

Abstract excerpt

OBJECTIVES: Host modifying factors, such as genetic predisposition, may increase severity of periodontitis. Genetic polymorphisms in interleukin-4 (IL-4) genes seem to influence host response to microbial challenge. Two IL-4 polymorphisms were found in association with asthma and atopy, and later with aggressive periodontitis in Caucasians. There seems to be a trend for racial differences regarding polymorphisms....

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Identifiers

PMID: 15001290
DOI: 10.1016/j.jdent.2003.11.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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