Article
[Risk factors in adult periodontitis: polymorphism in the interleukin-1 gene family].
Nederlands tijdschrift voor tandheelkunde - 1 Aug 2002
Laine M L, Farré M A, García-González M A, van Dijk L J, Ham A J, Winkel E G, Crusius J B A, Vandenbroucke J P, van Winkelhoff A J, Peña A S
Abstract excerpt
Interleukin (IL)-1 alpha, IL-1 beta and IL-1 receptor antagonist (ra) play a major role in regulation of the inflammatory response in periodontal tissues. The aim of this study was to investigate the distribution of genetic variation in the IL-1 gene family among periodontitis patients and controls, taking into account smoking and microbiology as additional variables. There were 53 non-smoking and 52 smoking...
Topics
- Adult
- Aggregatibacter actinomycetemcomitans
- Female
- Genetic Variation
- Humans
- Interleukin-1
- Male
- Middle Aged
- Periodontitis
- Polymorphism, Genetic
- Porphyromonas gingivalis