Article
Investigation of IL4 gene polymorphism in individuals with different levels of chronic periodontitis in a Brazilian population.
Journal of clinical periodontology - 1 Apr 2003
Scarel-Caminaga Raquel M, Trevilatto Paula C, Souza Ana P, Brito Rui B, Line Sergio R P
Abstract excerpt
BACKGROUND: Cytokines are key factors that mediate the inflammatory process during periodontal disease. Recent works have shown that the levels of cytokine expression are regulated by genetic polymorphisms, and that these variations can interfere with the progression of disease. The-590 (C-->T) p...
Topics
- Adult
- Alleles
- Black People
- Brazil
- Chi-Square Distribution
- Chronic Disease
- Cytosine
- Ethnicity
- Gene Expression Regulation
- Gene Frequency
- Genetic Predisposition to Disease
- Genetic Variation
- Genotype
- Humans
- Interleukin-4
- Periodontitis
- Polymorphism, Genetic
- Promoter Regions, Genetic