Polymorphisms and haplotypes in the interleukin-4 gene are associated with chronic periodontitis in a Brazilian population.

doi:10.1902/jop.2009.090392

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Polymorphisms and haplotypes in the interleukin-4 gene are associated with chronic periodontitis in a Brazilian population.

Journal of periodontology - 1 Mar 2010

Anovazzi Giovana, Kim Yeon J, Viana Aline C, Curtis Karen M C, Orrico Silvana R P, Cirelli Joni A, Scarel-Caminaga Raquel M

Abstract excerpt

BACKGROUND: Some haplotypes in the interleukin-4 (IL4) gene were reported to influence IL-4 cytokine production and were associated with inflammatory diseases. Association studies focusing on IL4 gene polymorphisms and periodontal disease provided conflicting results. The aim of this study is to investigate whether IL4 gene polymorphisms and haplotypes were related to chronic periodontitis in a Brazilian...

Topics

Adult
Age Factors
Brazil
Case-Control Studies
Chi-Square Distribution
Chronic Periodontitis
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-4

Likelihood Functions

Linkage Disequilibrium

Logistic Models

Male

Minisatellite Repeats

Source

Open in PubMed

Identifiers

PMID: 20192866
DOI: 10.1902/jop.2009.090392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20192866-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms and haplotypes in the interleukin-4 gene are associated with chronic periodontitis in a Brazilian population.PMID 20192866Read ↗

The association of interleukin-4 haplotypes with chronic periodontitis in a Czech population.Semantic proximity Read ↗

Association of haplotypes in the IL8 gene with susceptibility to chronic periodontitis in a Brazilian population.Semantic proximity Read ↗

[Association between -590C/T polymorphisms of interleukin-4 gene and chronic periodontitis: a meta-analysis].Semantic proximity Read ↗

Association of the polymorphisms in promoter and intron regions of the interleukin-4 gene with chronic periodontitis in a Turkish population.Semantic proximity Read ↗

Association between Polymorphisms in Interleukins 4 and 13 Genes and Chronic Periodontitis in a Han Chinese Population.Semantic proximity Read ↗

Interleukin 4 haplotypes of susceptibility to chronic periodontitis are associated with IL-4 protein levels but not with clinical outcomes of periodontal therapy.Semantic proximity Read ↗

Association between IL-4 and IL-4R Polymorphisms and Periodontitis: A Meta-Analysis.Semantic proximity Read ↗

Association between interleukin-1β C (3953/4)T polymorphism and chronic periodontitis: evidence from a meta-analysis.Semantic proximity Read ↗

Association between interleukin-4 gene -590 c/t, -33 c/t, and 70-base-pair polymorphisms and periodontitis susceptibility: a meta-analysis.Semantic proximity Read ↗

Interleukin-1β rs1143634 Polymorphism and Susceptibility to Periodontitis in the Iraqi Population.Semantic proximity Read ↗

IL4 gene polymorphisms and their relation to periodontal disease in a Macedonian population.Semantic proximity Read ↗

Two polymorphisms of interleukin-4 gene in Korean adult periodontitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.