Article
Interleukin-4 (C-590T) and interferon-gamma (G5644A) gene polymorphisms in patients with periodontitis.
Journal of periodontal research - 1 Feb 2008
Hooshmand B, Hajilooi M, Rafiei A, Mani-Kashani K H, Ghasemi R
Abstract excerpt
BACKGROUND AND OBJECTIVE: Periodontitis is a multifactorial disease and immunologic and genetic factors have an important role in its pathogenesis. Mutation in the promoter regions of the interleukin-4 and interferon-gamma genes has been reported to modify the protein expression. The objective of this study was to evaluate the possible role of interleukin-4 (C-590T) and interferon-gamma (G5644A) polymorphisms in...
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