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Article

Interleukin-4 (C-590T) and interferon-gamma (G5644A) gene polymorphisms in patients with periodontitis.

Journal of periodontal research - 1 Feb 2008

Hooshmand B, Hajilooi M, Rafiei A, Mani-Kashani K H, Ghasemi R

Abstract excerpt

BACKGROUND AND OBJECTIVE: Periodontitis is a multifactorial disease and immunologic and genetic factors have an important role in its pathogenesis. Mutation in the promoter regions of the interleukin-4 and interferon-gamma genes has been reported to modify the protein expression. The objective of...

Topics

Adolescent
Adult
Alleles
Chronic Disease
Epidemiologic Methods
Female
Genotype
Humans
Interferon-gamma
Interleukin-4
Iran
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Periodontitis

Polymorphism, Genetic

Source

Identifiers

PMID: 18230112
DOI: 10.1111/j.1600-0765.2007.01006.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-18230112-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Interleukin-4 (C-590T) and interferon-gamma (G5644A) gene polymorphisms in patients with periodontitis.PMID 18230112Read ↗

[Association between -590C/T polymorphisms of interleukin-4 gene and chronic periodontitis: a meta-analysis].Semantic proximity Read ↗

Association between interleukin-4 gene -590 c/t, -33 c/t, and 70-base-pair polymorphisms and periodontitis susceptibility: a meta-analysis.Semantic proximity Read ↗

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The interleukin-4 -34TT and -590TT genotype is correlated with increased expression and protein production in aggressive periodontitis.Semantic proximity Read ↗

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