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INTERLEUKIN-1 GENE POLYMORPHISMS AND SUSCEPTIBILITY TO PERIODONTITIS ACROSS ETHNICITIES AND POPULATIONS: A LITERATURE REVIEW.

Georgian medical news - 1 Apr 2026

Jahja E, Koçi A, Nakashidze I

Abstract excerpt

Periodontitis is a multifactorial inflammatory disease of the tooth-supporting tissues caused by dental biofilm and mediated by the host immune response. Interleukin-1 is a key pro-inflammatory cytokine implicated in periodontal inflammation, connective tissue breakdown, and disease progression. Beyond microbial and environmental factors, genetic polymorphisms affecting interleukin-1 activity contribute to...

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PMID: 42289112

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