Article
Association of the polymorphisms in promoter and intron regions of the interleukin-4 gene with chronic periodontitis in a Turkish population.
Acta odontologica Scandinavica - 1 Oct 2007
Kara Nurten, Keles Gonca Cayir, Sumer Pinar, Gunes Sezgin Ozgur, Bagci Hasan, Koprulu Hulya, Bek Yuksel
Abstract excerpt
OBJECTIVES: The etiology of periodontitis is related to the interaction between micro-organisms and host responses. Host modifying factors, such as genetic predisposition, may increase the severity of periodontitis. Recent works have shown that the levels of cytokine expression are regulated by genetic polymorphisms, and that these variations can interfere with progression of the disease. This study therefore...
Topics
- Adolescent
- Adult
- Aged
- Case-Control Studies
- Chronic Disease
- Gene Frequency
- Humans
- Interleukin-4
- Introns
- Male
- Middle Aged