Article
Estimation of relative fitnesses from relative risk data and the predicted future of haemoglobin alleles S and C
1 Jan 2004
Abstract excerpt
Epidemiological studies of genetic differences in disease susceptibility often estimate the relative risks (RR) of different genotypes. Here I provide an approach to calculate the relative fitnesses of different genotypes based on RR data so that population genetic approaches may be utilized with these data. Using recent RR data on human haemoglobin beta genotypes from Burkina Faso, this approach is used to...
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