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Article

Ancestral reconstruction and correlation of the frequencies of the hemoglobin S allele and the Duffy blood group alleles in human populations.

American journal of human biology : the official journal of the Human Biology Council - 1 Mar 2023

Ortega Diana Carolina, Cárdenas Heiber, González Ranulfo, Barreto Guillermo

Abstract excerpt

OBJECTIVES: Malaria is an important selective force for human genetic adaptation due to the sustained, lethal impact it has had on populations worldwide. High frequencies of both hemoglobin S and the null allele FYBES of the Duffy blood group have been found in areas where this disease is endemic, attributed to the protective action of the carriers of these variants against malaria infection. The objective of...

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PMID: 36376949
DOI: 10.1002/ajhb.23832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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