Article
3020insC NOD2/CARD15 polymorphism associated with treatment of colorectal cancer.
Medical oncology (Northwood, London, England) - 1 May 2014
Omrane Inés, Mezlini Amel, Baroudi Olfa, Stambouli Nejla, Bougatef Karim, Ayari Hager, Medimegh Imen, Bouzaienne Hassen, Uhrhammer Nancy, Bignon Yves-Jean, Benammar-Elgaaied Amel, Marrakchi Raja
Abstract excerpt
Chronic inflammation is closely linked to cancer. The risk of damage by colorectal cancer (CRC) may increase due to autoimmune disease and cryptogenic inflammation. Therefore, genetic factors implicated in the chronic irritation in inflammatory bowel disease such as NOD2/CARD15 may predispose to CRC. In this report, we shed the light on the possible contribution of the NOD2 3020insC variant to CRC risk in a...
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