Article
Absence of an essential role for thymic stromal lymphopoietin receptor in murine B-cell development.
Molecular and cellular biology - 1 Mar 2004
Carpino Nick, Thierfelder William E, Chang Ming-shi, Saris Chris, Turner Steven J, Ziegler Steven F, Ihle James N
Abstract excerpt
The murine cytokine thymic stromal lymphopoietin (TSLP) supports the development of B220+ IgM+ immature B cells and induces thymocyte proliferation in vitro. Human TSLP, by contrast, activates CD11c+ dendritic cells, but not B or T cells. Recent studies have demonstrated that the receptor for TSLP consists of a heterodimer of the interleukin 7 (IL-7) alpha chain and a novel protein that resembles the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
