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Article

Structural effects of an LQT-3 mutation on heart Na+ channel gating.

Biophysical journal - 1 Mar 2004

Tateyama M, Liu H, Yang A-S, Cormier J W, Kass R S

Abstract excerpt

Computational methods that predict three-dimensional structures from amino acid sequences have become increasingly accurate and have provided insights into structure-function relationships for proteins in the absence of structural data. However, the accuracy of computational structural models requires experimental approaches for validation. Here we report direct testing of the predictions of a previously reported...

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Share to Ion Channel Gating
Share to Membrane Potentials
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Myocytes, Cardiac

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Source

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Identifiers

PMID: 14990510
DOI: 10.1016/S0006-3495(04)74251-4
PMCID: PMC1304018

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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