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Article

A novel LQT3 mutation implicates the human cardiac sodium channel domain IVS6 in inactivation kinetics.

Cardiovascular research - 15 Mar 2003

Groenewegen W Antoinette, Bezzina Connie R, van Tintelen J Peter, Hoorntje Theo M, Mannens Marcel M A M, Wilde Arthur A M, Jongsma Habo J, Rook Martin B

Abstract excerpt

UNLABELLED: The Long QT3 syndrome is associated with mutations in the cardiac sodium channel gene SCN5A. OBJECTIVE: The aim of the present study was the identification and functional characterization of a mutation in a family with the long QT3 syndrome. METHODS: The human cardiac sodium channel gene SCN5A was screened for mutations by single-stranded conformation polymorphism. The functional consequences of...

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Source

Identifiers

PMID: 12650885
DOI: 10.1016/s0008-6363(02)00838-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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