Article
Multigene reverse transcription-PCR profiling of circulating tumor cells in hormone-refractory prostate cancer.
Clinical chemistry - 1 May 2004
O'Hara S Mark, Moreno Jose G, Zweitzig Daniel R, Gross Steve, Gomella Leonard G, Terstappen Leon W M M
Abstract excerpt
BACKGROUND: Circulating tumor cells (CTCs) represent a surrogate source of tissue and conceptually represent a "real-time" biopsy. We previously reported that the number of CTCs mirrors disease progression in hormone-refractory prostate cancer (HRPC). To improve characterization of CTCs we further investigated whether in vitro transcription-based multigene reverse transcription-PCR expression profiles could be...
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