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Isolation and genomic analysis of circulating tumor cells from castration resistant metastatic prostate cancer

28 Feb 2012

Abstract excerpt

BACKGROUND: The number of circulating tumor cells (CTCs) in metastatic prostate cancer patients provides prognostic and predictive information. However, it is the molecular characterization of CTCs that offers insight into the biology of these tumor cells in the context of personalized treatment. METHODS: We developed a novel approach to isolate CTCs away from hematopoietic cells with high purity, enabling...

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PMID: 22373240
DOI: 10.1186/1471-2407-12-78

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