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Article

Proliferation of Microglia, but not Photoreceptors, in the Outer Nuclear Layer of the<i>rd-1</i>Mouse

25 Feb 2004

Abstract excerpt

PURPOSE: To establish whether photoreceptor apoptosis in the rd-1 mouse is accompanied by cell cycle progression. Studies of cell cycle proteins in other models of neuronal death provide consistent evidence that a repertoire of proliferative markers accompanies apoptosis. METHODS: The spatiotemporal progression of photoreceptor loss in rd-1 and control mice at postnatal days (PN)8, -10, -12, -15, and -18 was...

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Identifiers

PMID: 14985319
DOI: 10.1167/iovs.03-0301

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