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Article

Activation of caspase-3 during degeneration of the outer nuclear layer in the rd mouse retina.

Ophthalmic research - 1 Jan 2000

Kim Dong-Hwan, Kim Jeong-a, Choi Jun-Sub, Joo Choun-Ki

Abstract excerpt

Caspase activation has been implicated in apoptosis, and the nature of the apoptotic stimulus determines the specific caspase activation during apoptosis. In this study, we examined the activation of caspase-3 during photoreceptor degeneration in the rd mouse, which has a mutation on a gene encoding cyclic GMP phosphodiesterase. The outer nuclear layer of the rd mouse retina was observed using light and electron...

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Identifiers

PMID: 12097798
DOI: 10.1159/000063659

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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