Article
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients.
Molecular genetics and metabolism - 1 Nov 2009
Marchegiani Francesca, Spazzafumo Liana, Provinciali Mauro, Cardelli Maurizio, Olivieri Fabiola, Franceschi Claudio, Lattanzio Fabrizia, Antonicelli Roberto
Abstract excerpt
It is well known that oxidative stress plays an important role in atherosclerosis and age-related diseases. The antioxidant properties of the Human Paraoxonase gene family (PON1, 2, 3) have been widely investigated, as well as a possible role of the such gene family in cardiovascular disease. In this study, we investigated the relationship between the C311S PON2 polymorphism and the prognosis of acute myocardial...
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