Article
The replication error phenotype is associated with the development of distant metastases in hormonally treated patients with breast carcinoma.
Cancer - 1 Mar 2004
Chagpar Anees, Magliocco Anthony, Kerviche Annette, Tan Leonard, Walley Barbara, DeCoteau John F
Abstract excerpt
BACKGROUND: The positive replication error (RER+) phenotype defines a distinct subgroup of tumors with specific clinical, pathologic, and molecular features that have been documented well in hereditary nonpolyposis colon carcinoma (HNPCC). More recently, this phenotype also has been described in breast carcinoma. METHODS: To determine the effect of RER phenotype on prognosis in patients with breast carcinoma, the...
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