Article
Differential roles of multiple signal peptidases in the virulence of Listeria monocytogenes.
Molecular microbiology - 1 Mar 2004
Bonnemain Claire, Raynaud Catherine, Réglier-Poupet Hélène, Dubail Iharilalao, Frehel Claude, Lety Marie-Annick, Berche Patrick, Charbit Alain
Abstract excerpt
Most bacteria contain one type I signal peptidase (Spase I) for cleavage of signal peptides from exported and secreted proteins. Here, we identified a locus encoding three contiguous Spase I genes in the genome of Listeria monocytogenes. The deduced Sip proteins (denoted SipX, SipY and SipZ) are significantly similar to SipS and SipT, the major SPase I proteins of Bacillus subtilis (38% to 44% peptidic identity)....
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