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Article

Pseudomonas aeruginosa possesses two putative type I signal peptidases, LepB and PA1303, each with distinct roles in physiology and virulence.

Journal of bacteriology - 1 Sept 2012

Waite Richard D, Rose Ruth S, Rangarajan Minnie, Aduse-Opoku Joseph, Hashim Ahmed, Curtis Michael A

Abstract excerpt

Type I signal peptidases (SPases) cleave signal peptides from proteins during translocation across biological membranes and hence play a vital role in cellular physiology. SPase activity is also of fundamental importance to the pathogenesis of infection for many bacteria, including Pseudomonas aeruginosa, which utilizes a variety of secreted virulence factors, such as proteases and toxins. P. aeruginosa possesses...

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Identifiers

PMID: 22730125
DOI: 10.1128/JB.06678-11
PMCID: PMC3415513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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