Article
Characterization of an extracellular virulence factor made by group A Streptococcus with homology to the Listeria monocytogenes internalin family of proteins.
Infection and immunity - 1 Dec 2003
Reid Sean D, Montgomery Alison G, Voyich Jovanka M, DeLeo Frank R, Lei Benfang, Ireland Robin M, Green Nicole M, Liu Mengyao, Lukomski Slawomir, Musser James M
Abstract excerpt
Leucine-rich repeats (LRR) characterize a diverse array of proteins and function to provide a versatile framework for protein-protein interactions. Importantly, each of the bacterial LRR proteins that have been well described, including those of Listeria monocytogenes, Yersinia pestis, and Shigella flexneri, have been implicated in virulence. Here we describe an 87.4-kDa group A Streptococcus (GAS) protein...
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