Article
A survival method to estimate the time to occurrence of mutations: an application to thymidine analogue mutations in HIV-1-infected patients.
The Journal of infectious diseases - 1 Mar 2004
Flandre Philippe, Descamps Diane, Joly Veronique, Meiffredy Vincent, Tamalet Catherine, Izopet Jacques, Brun-Vezinet Francoise
Abstract excerpt
Virologic studies of human immunodeficiency virus type 1-infected patients have investigated either the emergence of resistance mutations according to the treatment received (type I) or their effect on subsequent regimens (type II). Type I studies provide an estimation of the frequency distributi...
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