Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of Pharmacogenetic Markers with Premature Discontinuation of First-line Anti-HIV Therapy: An Observational Cohort Study

10 Dec 2010

Abstract excerpt

BACKGROUND: Poor tolerance and adverse drug reactions are main reasons for discontinuation of antiretroviral therapy (ART). Identifying predictors of ART discontinuation is a priority in HIV care. METHODS: A genetic association study in an observational cohort to evaluate the association of pharmacogenetic markers with time to treatment discontinuation during the first year of ART. Analysis included 577...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Research and Disease Studies
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21288825
DOI: 10.1093/infdis/jiq043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of Pharmacogenetic Markers with Premature Discontinuation of First-line Anti-HIV Therapy: An Observational Cohort StudyPMID 21288825Read ↗

Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis.Semantic proximity Read ↗

The role of pharmacogenomics in the discontinuation of psychotropic medication: a scoping review protocolSemantic proximity Read ↗

The role of pharmacogenomics in the discontinuation of psychotropic medication: a scoping review protocolSemantic proximity Read ↗

Pharmacogenetics of plasma efavirenz exposure after treatment discontinuation: an Adult AIDS Clinical Trials Group Study.Semantic proximity Read ↗

Genotype influences antidepressant discontinuation in a pre-emptive pharmacogenetic testing population.Semantic proximity Read ↗

Predictive variables of sustained virological response after early discontinuation of triple therapy with telaprevir for genotype-1 HCV infection.Semantic proximity Read ↗

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.Semantic proximity Read ↗

Predictors of early treatment discontinuation among patients with genotype 1 hepatitis C and implications for viral eradication.Semantic proximity Read ↗

Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenz-containing regimens.Semantic proximity Read ↗

Pharmacogenetics of efavirenz discontinuation for reported central nervous system symptoms appears to differ by race.Semantic proximity Read ↗

Variability in the plasma concentration of efavirenz and nevirapine is associated with genotypic resistance after treatment interruption.Semantic proximity Read ↗

CYP2B6 G516T genotyping in a UK cohort of HIV-positive patients: polymorphism frequency and influence on efavirenz discontinuation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.