Article
Plexina1 autoinhibition by the plexin sema domain.
Neuron - 1 Feb 2001
Takahashi T, Strittmatter S M
Abstract excerpt
Semaphorin 3A (Sema3A) binds to neuropilin-1 (NP1) and activates the transmembrane Plexin to transduce a repulsive axon guidance signal. Here, we show that Sema3 signals are transduced equally effectively by PlexinA1 or PlexinA2, but not by PlexinA3. Deletion analysis of the PlexinA1 ectodomain d...
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