Article
The Drosophila receptor guanylyl cyclase Gyc76C is required for semaphorin-1a-plexin A-mediated axonal repulsion.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 28 Jul 2004
Ayoob Joseph C, Yu Hung-Hsiang, Terman Jonathan R, Kolodkin Alex L
Abstract excerpt
Cyclic nucleotide levels within extending growth cones influence how navigating axons respond to guidance cues. Pharmacological alteration of cAMP or cGMP signaling in vitro dramatically modulates how growth cones respond to attractants and repellents, although how these second messengers function in the context of guidance cue signaling cascades in vivo is poorly understood. We report here that the Drosophila...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
