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Article

Genome-wide linkage analysis of systolic blood pressure slope using the Genetic Analysis Workshop 13 data sets.

BMC genetics - 31 Dec 2003

Pinnaduwage Dushanthi, Beyene Joseph, Fallah Shafagh

Abstract excerpt

Systolic blood pressure (SBP) is an age-dependent complex trait for which both environmental and genetic factors may play a role in explaining variability among individuals. We performed a genome-wide scan of the rate of change in SBP over time on the Framingham Heart Study data and one randomly selected replicate of the simulated data from the Genetic Analysis Workshop 13. We used a variance-component model to...

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PMID: 14975154
DOI: 10.1186/1471-2156-4-S1-S86
PMCID: PMC1866526

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