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Article

Multivariate sib-pair linkage analysis of longitudinal phenotypes by three step-wise analysis approaches.

BMC genetics - 31 Dec 2003

Guo Zheng, Li Xia, Rao Shaoqi, Moser Kathy L, Zhang Tianwen, Gong Binsheng, Shen Gongqing, Li Lin, Cannata Ruth, Zirzow Erich, Topol Eric J, Wang Qing

Abstract excerpt

BACKGROUND: Current statistical methods for sib-pair linkage analysis of complex diseases include linear models, generalized linear models, and novel data mining techniques. The purpose of this study was to further investigate the utility and properties of a novel pattern recognition technique (step-wise discriminant analysis) using the chromosome 10 linkage data from the Framingham Heart Study and by comparing...

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Identifiers

PMID: 14975136
DOI: 10.1186/1471-2156-4-S1-S68
PMCID: PMC1866506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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