Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An examination of the genotyping error detection function of SIMWALK2.

BMC genetics - 31 Dec 2003

Badzioch Michael D, DeFrance Hawkins B, Jarvik Gail P

Abstract excerpt

This investigation was undertaken to assess the sensitivity and specificity of the genotyping error detection function of the computer program SIMWALK2. We chose to examine chromosome 22, which had 7 microsatellite markers, from a single simulated replicate (330 pedigrees with a pattern of missing genotype data similar to the Framingham families). We created genotype errors at five overall frequencies (0.0,...

Topics

Adult Children
Bias
Cardiovascular Diseases
Computer Simulation
Female
Genotype
Humans
Male
Nuclear Family
Pedigree
Reproducibility of Results
Software

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 14975108
DOI: 10.1186/1471-2156-4-S1-S40
PMCID: PMC1866476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An examination of the genotyping error detection function of SIMWALK2.PMID 14975108Read ↗

Comparative study of multipoint methods for genotype error detection.Semantic proximity Read ↗

Pedigree and genotype errors in the Framingham Heart Study.Semantic proximity Read ↗

Genotyping errors, pedigree errors, and missing data.Semantic proximity Read ↗

Genotyping errors: causes, consequences and solutions.Semantic proximity Read ↗

True pedigree errors more frequent than apparent errors for single nucleotide polymorphisms.Semantic proximity Read ↗

Simultaneous estimation of genotype error and uncalled deletion rates in whole genome sequence dataSemantic proximity Read ↗

Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods.Semantic proximity Read ↗

The effect of genotyping error in sib-pair genomewide linkage scans depends crucially upon the method of analysis.Semantic proximity Read ↗

Identification and analysis of error types in high-throughput genotyping.Semantic proximity Read ↗

Assessing the impact of differential genotyping errors on rare variant tests of association.Semantic proximity Read ↗

Incorporating individual error rate into association test of unmatched case-control design.Semantic proximity Read ↗

The reliability of haplotyping inference in nuclear families: misassignment rates for SNPs and microsatellites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.