Article
Consistency of linkage results across exams and methods in the Framingham Heart Study.
BMC genetics - 31 Dec 2003
Atwood Larry D, Heard-Costa Nancy L, Cupples L Adrienne, Levy Daniel
Abstract excerpt
BACKGROUND: The repeated measures in the Framingham Heart Study in the Genetic Analysis Workshop 13 data set allow us to test for consistency of linkage results within a study across time. We compared regression-based linkage to variance components linkage across time for six quantitative traits in the real data. RESULTS: The variance components approach found 11 significant linkages, the regression-based...
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