Article
Comparison of the linkage results of two phenotypic constructs from longitudinal data in the Framingham Heart Study: analyses on data measured at three time points and on the average of three measurements.
BMC genetics - 31 Dec 2003
Cheng Rong, Park Naeun, Hodge Susan E, Juo Suh-Hang Hank
Abstract excerpt
BACKGROUND: Family studies are often conducted in a cross-sectional manner without long-term follow-up data. The relative contribution of a gene to a specific trait could change over the lifetime. The Framingham Heart Study offers a unique opportunity to investigate potential gene x time interaction. We performed linkage analysis on the body mass index (BMI) measured in 1970, 1978, and 1986 for this project....
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