Article
Power of linkage analysis using traits generated from simulated longitudinal data of the Framingham Heart Study.
BMC genetics - 31 Dec 2003
Wang Dai, Li Xiaohui, Lin Ying-Chao, Yang Kai, Guo Xiuqing, Yang Huiying
Abstract excerpt
The Framingham Heart Study is a very successful longitudinal research for cardiovascular diseases. The completion of a 10-cM genome scan in Framingham families provided an opportunity to evaluate linkage using longitudinal data. Several descriptive traits based on simulated longitudinal data from the Genetic Analysis Workshop 13 (GAW13) were generated, and linkage analyses were performed for these traits. We...
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