Article
Analysis of binary traits: testing association in the presence of linkage.
BMC genetics - 30 Dec 2005
Jonasdottir Gudrun, Palmgren Juni, Humphreys Keith
Abstract excerpt
Most methods for testing association in the presence of linkage, using family-based studies, have been developed for continuous traits. FBAT (family-based association tests) is one of few methods appropriate for discrete outcomes. In this article we describe a new test of association in the presence of linkage for binary traits. We use a gamma random effects model in which association and linkage are modelled as...
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