Article
Molecular epidemiology of malaria in cameroon. IX. Characteristics of recrudescent and persistent Plasmodium falciparum infections after chloroquine or amodiaquine treatment in children.
The American journal of tropical medicine and hygiene - 1 Feb 2002
Basco Leonardo K, Ndounga Mathieu, Keundjian Annick, Ringwald Pascal
Abstract excerpt
In the absence of a firmly established gene responsible for chloroquine and amodiaquine resistance in Plasmodium falciparum, surveillance of resistance to these first-line drugs in Cameroon needs to be performed by in vivo or in vitro tests for drug resistance. These 2 methodological approaches to define drug resistance were shown to be complementary and concordant in a majority of cases at our study sites, but...
Topics
- Amodiaquine
- Animals
- Antimalarials
- Cameroon
- Child, Preschool
- Chloroquine
- Chromatography, High Pressure Liquid
- DNA Primers
- DNA, Protozoan
- Drug Resistance
- Female
- Genotype
- Humans