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Article

Virus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domain.

Journal of virology - 1 Feb 2005

Scholz Isabel, Arvidson Brian, Huseby Doug, Barklis Eric

Abstract excerpt

The N-terminal domains (NTDs) of the human immunodeficiency virus type 1 (HIV-1) capsid (CA) protein have been modeled to form hexamer rings in the mature cores of virions. In vitro, hexamer ring units organize into either tubes or spheres, in a pH-dependent fashion. To probe factors which might govern hexamer assembly preferences in vivo, we examined the effects of mutations at CA histidine residue 84 (H84),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15650173
DOI: 10.1128/JVI.79.3.1470-1479.2005
PMCID: PMC544128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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