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Article

Specificity of interaction of INI1/hSNF5 with retroviral integrases and its functional significance.

Journal of virology - 1 Mar 2004

Yung Eric, Sorin Masha, Wang Emilie-Jeanne, Perumal Seena, Ott David, Kalpana Ganjam V

Abstract excerpt

Integrase interactor 1 (INI1)/hSNF5 is a host factor that directly interacts with human immunodeficiency virus type 1 (HIV-1) integrase and is incorporated into HIV-1 virions. Here, we show that while INI1/hSNF5 is completely absent from purified microvesicular fractions, it is specifically incorporated into HIV-1 virions with an integrase-to-INI1/hSNF5 stoichiometry of approximately 2:1 (molar ratio). In...

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Source

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Identifiers

PMID: 14963118
DOI: 10.1128/jvi.78.5.2222-2231.2004
PMCID: PMC369229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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